Volume 11 Issue 3
Jun.  2018
Turn off MathJax
Article Contents
Chinese Optics  > 2018  >  11(3): 459-474.
ZHU Shan-shan, LU Jiao, LIU He-nan, CHEN Shuo, ZENG Zhu, QIAN Wei, CHEN Xiao-long. Advances in applications of biomedical photonics in diabetic retinopathy[J]. Chinese Optics, 2018, 11(3): 459-474. doi: 10.3788/CO.20181103.0459
Citation: ZHU Shan-shan, LU Jiao, LIU He-nan, CHEN Shuo, ZENG Zhu, QIAN Wei, CHEN Xiao-long. Advances in applications of biomedical photonics in diabetic retinopathy[J]. Chinese Optics, 2018, 11(3): 459-474. doi: 10.3788/CO.20181103.0459
shu

Advances in applications of biomedical photonics in diabetic retinopathy

  • 1.

    Sino-Dutch Biomedical and Information Engineering School, Northeastern University, Shenyang 110167, China

  • 2.

    Department of Ophthalmology, Shengjing Hospital, China Medical University, Shenyang 110004, China

  • 3.

    School of Biology and Engineering, Guizhou Medical University, Guiyang 550004, China

Funds:

National Natural Science Foundation of China 61605025

National Natural Science Foundation of China 61501101

the Fundamental Research Funds for the Central Universities 171902001

Program for Innovation Talents in Universities of Liaoning Province LR2016031

More Information
    Abstract
  • Diabetic Retinopathy(DR), as the most common complication of diabetes, has become one of the leading cause of vision loss or blindness. More than 50% of the patients with visual impairment or blindness as a result of DR can be prevented by early diagnosis and prompt treatment. Therefore, it is of great clinical significance to study the diagnosis and treatment of DR. Based on the structural and optical properties of eyes, biomedical photonics techniques have been widely used in diagnosis and treatment of DR and show great prospects. In this paper, the principle of biomedical photonics techniques in clinical diagnosis and treatment of DR is reviewed and the characteristics of each technique is analyzed and compared. Finally, the development trend of biomedical photonics technology in clinical DR diagnosis and treatment is prospected.

     

    • FullText(HTML)
  • loading
    • References(97)
  • [1]
    XU Y, WANG L, HE J, et al.. Prevalence and control of diabetes in Chinese adults[J]. JAMA, 2013, 310(9):948-958. doi: 10.1001/jama.2013.168118
    [2]
    中华医学会眼科学会眼底病学组.我国糖尿病视网膜病变临床诊疗指南(2014)[J].中华眼科杂志, 2014, 50(11):851-865. doi: 10.3760/cma.j.issn.0412-4081.2014.11.014

    The Chinese Academy of Ophthalmology Eye Disease Study Group. Clinical guidelines for diagnosis and treatment of diabetic retinopathy in China(2014)[J]. Chinese Journal of Ophthalmology, 2014, 50(11):851-865.(in Chinese) doi: 10.3760/cma.j.issn.0412-4081.2014.11.014
    [3]
    CHEUNG N, MITCHELL P, WONG T Y. Diabetic retinopathy[J]. The LANCET, 2010, 376(9735):126-134.
    [4]
    EBNETR A, ZINKERNAGEL M S. Novelties in diabetic retinopathy[J]. Endocrine Development, 2015, 31:84-96. http://cn.bing.com/academic/profile?id=83da0d3da1caa499bbcd2a2406ca3c28&encoded=0&v=paper_preview&mkt=zh-cn
    [5]
    徐可欣, 高峰, 赵会娟.生物医学光子学(第2版)[M].北京:科学出版社, 2011.

    XU K X, GAO F, ZHAO H J. Biomedical Photonics(the second edition)[M]. Beijing:Science Press, 2011.(in Chinese)
    [6]
    PARK Y G, ROH Y J. New diagnostic and therapeutic approaches for preventing the progression of diabetic retinopathy[J]. Journal of Diabetes Research, 2015, 2016(4):1753584. http://cn.bing.com/academic/profile?id=c47e1be68b8a5b6e7099e108d91bec80&encoded=0&v=paper_preview&mkt=zh-cn
    [7]
    The Diabetic Retinopathy Study Research Group. Photocoagulation treatment of proliferative diabetic retinopathy[J]. Ophthalmology, 1981, 88(7):583-600. doi: 10.1016/S0161-6420(81)34978-1
    [8]
    Early Treatment Diabetic Retinopathy Study Research Group. Early photocoagulation for diabetic retinopathy. ETDRS report number 9[J]. Ophthalmology, 1991, 98(5):766-785. doi: 10.1016/S0161-6420(13)38011-7
    [9]
    MOHAMED Q, GILLIES M C, WONG T Y. Management of diabetic retinopathy:a systematic review[J]. JAMA, 2007, 298(8):902-916. doi: 10.1001/jama.298.8.902
    [10]
    MARTONY C L, BAHN C F, MEYER R F. Slit Lamp:Examination and Photography[M]. Sedona, A Z:Time-One Ink Ltd, 2007.
    [11]
    KHALAF S S, ALBDOUR M D, ALTILL M I. Clinical biomicroscopy versus fluorescein angiography:effectiveness and sensitivity in detecting diabetic retinopathy[J]. European Journal of Ophthalmology, 2007, 17(1):84-88. doi: 10.1177/112067210701700112
    [12]
    NANDA D, SARKAR M, SAHU V, et al.. Comparing between slit-lamp biomicroscopy and fluorescein angiography in diagnosing diabetic retinopathy[J]. Scholars Journal of Applied Medical Sciences, 2017, 5(1B):108-111. http://cn.bing.com/academic/profile?id=41d97067153f8bf273921fefeb1825a9&encoded=0&v=paper_preview&mkt=zh-cn
    [13]
    崔桂华.眼底照相机光学系统中杂光和鬼像的控制[J].光学技术, 2000, 26(2):139-141. http://www.cnki.com.cn/Article/CJFDTOTAL-GXJS200002015.htm

    CUI G H. Control of ghost and scatter light in retinal camera[J]. Optical Technique, 2000, 26(2):139-141.(in Chinese) http://www.cnki.com.cn/Article/CJFDTOTAL-GXJS200002015.htm
    [14]
    SHIRAKI K, HARIMURA Y, MORIWAKI M, et al.. Digital fluoresce in fundus angiography with DFC-512 and IMAGEnet systems[J]. European Journal of Ophthalmoogyl, 1991, 1(1):39-44. doi: 10.1177/112067219100100108
    [15]
    霍妍佼, 魏文斌.眼底成像技术新进展——共聚焦激光扫描检眼镜[J].国际眼科纵览, 2015, 39(4):224-228. http://www.docin.com/p-1359224335.html

    HUO Y J, WEI W B. Progress in fundus imaging:confocal scanning laser opthalmoscope[J]. International Review of Ophthalmology, 2015, 39(4):224-228.(in Chinese) http://www.docin.com/p-1359224335.html
    [16]
    FOPS T J B, MMEDSCI C J B. Ophthalmic imaging today:an ophthalmic photographer's viewpoint-a review[J]. Clinical and Experimental Ophthalmology, 2010, 37(1):2-13. http://cn.bing.com/academic/profile?id=3e0026e2665c0a0c45355f02a571f045&encoded=0&v=paper_preview&mkt=zh-cn
    [17]
    李芙蓉, 袁宏志, 张鑫, 等.彩色眼底照相在糖尿病视网膜病变早期筛查中的意义[J].宁夏医学杂志, 2012, 34(9):918-920. http://mall.cnki.net/magazine/article/NXYX201209051.htm

    LI F R, YUAN H ZH, ZHANG X, et al.. The value of color fundus photography in early diabetic retinopathy screening[J]. Ningxia Medical Journal, 2012, 34(9):918-920.(in Chinese) http://mall.cnki.net/magazine/article/NXYX201209051.htm
    [18]
    白宁艳, 刘雪莲, 徐浩, 等.眼底彩色照相在糖尿病性视网膜病变筛查中的应用[J].中华实用医药杂志, 2009, 9(6):449-450. http://journal.9med.net/upload/201003251258026302.pdf

    BAI N Y, LIU X L, XU H, et al.. The application of color fundus photography in diabetic retinopathy screening[J]. Chinese Journal of Practical Medicine, 2009, 9(6):449-450.(in Chinese) http://journal.9med.net/upload/201003251258026302.pdf
    [19]
    张蕾, 许维强, 谭荣强, 等.糖尿病视网膜病变筛查方式探讨[J].国际眼科杂志, 2010, 10(3):482-484. http://journal.9med.net/html/qikan/wgkx/gjykzz/20103103/lclz/20100513094327474_527396.html

    ZHANG L, XU W Q, TAN R Q, et al.. Study of diabetic retinopathy screening modes[J]. International Journal of Ophthalmology, 2010, 10(3):482-484.(in Chinese) http://journal.9med.net/html/qikan/wgkx/gjykzz/20103103/lclz/20100513094327474_527396.html
    [20]
    全国眼底病协作组.糖尿病视网膜病变分期标准[J].中华眼科杂志, 1985, 21:113. http://industry.wanfangdata.com.cn/dl/Detail/NSTLQK?id=NSTLQK_10.2217-fon.10.26

    National group of ocular fundus disease. Standard of diabetic retinopathy grading[J]. Chinese Journal of Ophthalmology, 1985, 21:113.(in Chinese) http://industry.wanfangdata.com.cn/dl/Detail/NSTLQK?id=NSTLQK_10.2217-fon.10.26
    [21]
    ROSSES A P O, BEN A J, de SOUZA C F, et al.. Diagnostic performance of retinal digital photography for diabetic retinopathy screening in primary care[J]. Family Practice, 2017, 34(5):546-551. doi: 10.1093/fampra/cmx020
    [22]
    GULSHAN V, PENG L, CORAM M, et al.. Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs[J]. JAMA, 2016, 316(22):2402-2410. doi: 10.1001/jama.2016.17216
    [23]
    WEBB R H, HUGHES G W, POMERANTZEFF O. Flying spot TV ophthalmoscope[J]. Applied Optics, 1980, 19(17):2991-2996. doi: 10.1364/AO.19.002991
    [24]
    MAINSTER M A, TIMBERLAKE G T, WEBB R H, et al.. Scanning laser ophthalmoscopy:clinical applications[J]. Ophthalmology, 1982, 89(7):852-857. doi: 10.1016/S0161-6420(82)34714-4
    [25]
    冯绍鸿, 徐丽.扫描激光检眼镜的基本原理及其临床应用[J].中国实用眼科杂志, 1999, 15(4):199-201. http://www.doc88.com/p-3853717954935.html

    FENG SH H, XU L. The basic principle and clinical application of scanning laser ophthalmoscope[J]. Chinese Journal of Practical Ophthalmology, 1999, 15(4):199-201.(in Chinese) http://www.doc88.com/p-3853717954935.html
    [26]
    WEBB R H, HUGHES G W, DELORI F C. Confocal scanning laser ophthalmoscope[J]. Applied Optics, 1987, 26(8):1492-1499. doi: 10.1364/AO.26.001492
    [27]
    SHARP P F, MANIVANNAN A. The scanning laser ophthalmoscope[J]. Physics in Medicine and Biology, 1997, 42(5):951-966. doi: 10.1088/0031-9155/42/5/014
    [28]
    KIRKPATRICK J N, MANIVANNAN A, GUPTA A K, et al.. Fundus imaging in patients with cataract:role for a variable wavelength scanning laser ophthalmoscope[J]. British Journal of Ophthalmology, 1995, 79(10):892-899. doi: 10.1136/bjo.79.10.892
    [29]
    ETTEN P G, BROUWERE D D, WESTERS P, et al.. Zero dilation ophthalmoscopy[J]. The Journal of Ophthalmic Photography, 2014, 36(2):55-62. http://cn.bing.com/academic/profile?id=8c1e43de9a3067e367c3ff0e007b7298&encoded=0&v=paper_preview&mkt=zh-cn
    [30]
    ZHU S, TRIEST M V, TONG M, et al.. Retinal vascular tortuosity in hospitalized patients with type 2 diabetes and diabetic retinopathy in China[J]. Journal of Biomedical Science and Engineering, 2016, 9(10):143-154. doi: 10.4236/jbise.2016.910B019
    [31]
    BEKKERS E J, ZHANG J, DUITS R, et al. . Curvature based biomarkers for diabetic retinopathy via exponential curve fits in SE(2)[C]. Ophthalmic Medical Image Analysis Second International Workshop, Munich, Germany, 2015: 113-120.
    [32]
    ROMENY B M H, BEKKERS E J, ZHANG J, et al.. Brain-inspired algorithms for retinal image analysis[J]. Machine Vision and Applications, 2016, 27(8):1117-1135. doi: 10.1007/s00138-016-0771-9
    [33]
    SILVA P S, CAVALLERANO J D, SUN J K, et al.. Nomydriatic ultrawide field retinal imaging compared with dilated standard 7-field 35mm photography and retinal specialist examination for evaluation of diabetic retinopathy[J]. American Journal of Ophthalmology, 2012, 154(3):549-559. doi: 10.1016/j.ajo.2012.03.019
    [34]
    KERNT M, HADI I, PINTER F, et al.. Assessment of diabetic retinopathy using nonmydriatic ultra-widefield scanning laser ophthalmoscopy(Optomap) compared with ETDRS 7-field stereo photography[J]. Diabetes Care, 2012, 35:2459-2463. doi: 10.2337/dc12-0346
    [35]
    HUSSAIN N, EDRAKI M, TAHHAN R, et al.. Telemedicine for diabetic retinopathy screening using an ultra-widefield fundus camera[J]. Clinical Ophthalmology, 2017, 11:1477-1482. doi: 10.2147/OPTH
    [36]
    葛婧菁.便携式双波段荧光眼底血管造影仪的光学设计[J].中国光学, 2013, 6(2):223-230. http://www.chineseoptics.net.cn/CN/abstract/abstract8958.shtml

    GE J J. Optical design of portable dual-band fluorescence fundus angiography[J]. Chinese Optics, 2013, 6(2):223-230.(in Chinese) http://www.chineseoptics.net.cn/CN/abstract/abstract8958.shtml
    [37]
    王霞, 裴承华, 丁爱东.眼底荧光血管造影对早期诊断糖尿病性视网膜病变的意义[J].中国医药科学, 2014, 10(16):211-212. doi: 10.3969/j.issn.2095-0616.2014.16.073

    WANG X, PEI CH H, DING A D. Fundus fluorescein angiography in the early diagnosis of diabetic retinopathy significance[J]. China Medicine and Pharmacy, 2014, 10(16):211-212.(in Chinese) doi: 10.3969/j.issn.2095-0616.2014.16.073
    [38]
    余兆敏, 宋卫平, 邓晓.眼底荧光血管造影在糖尿病性视网膜病变中的临床应用[J].中国医学工程, 2015(10):86-89. http://www.cqvip.com/QK/87361X/201510/666559526.html

    YU ZH M, SONG W P, DENG X. Clinical application of fundus fluorescence angiography in diabetic retinopathy[J]. China Medical Engineering, 2015(10):86-89.(in Chinese) http://www.cqvip.com/QK/87361X/201510/666559526.html
    [39]
    XU D, ZHANG X H, SUN Z, et al.. Evaluating fundus photography and fundus fluorescein angiography in the grading of diabetic retinopathy[J]. Chinese Journal of Experimental Ophthalmology, 2013, 31(8):779-782. http://cn.bing.com/academic/profile?id=0afa132455cf61516a4d5f782292ceb2&encoded=0&v=paper_preview&mkt=zh-cn
    [40]
    WESSEL M M, AAKER G D, PARLITSIS G, et al.. Ultra-wide-field angiography improves the detection and classification of diabetic retinopathy[J]. Retina, 2012, 32(4):785-791. doi: 10.1097/IAE.0b013e3182278b64
    [41]
    WESSEL M M, NAIR N, AAKER G D, et al.. Peripheral retinal ischaemia, as evaluated by ultra-widefield fluorescein angiography, is associated with diabetic macular oedema[J]. British Journal of Ophthalmology, 2012, 96:694-698. doi: 10.1136/bjophthalmol-2011-300774
    [42]
    PATEL R D, MESSNER L V, TEITELBAUM B, et al.. Characterization of ischemic index using ultra-widefield fluorescein angiography in patients with focal and diffuse recalcitrant diabetic macular edema[J]. American Journal of Ophthalmology, 2013, 155(6):1038-1044. doi: 10.1016/j.ajo.2013.01.007
    [43]
    SIM D A, KEANE P A, RAJENDRAM R, et al.. Patterns of peripheral retinal and central macula ischemia in diabetic retinopathy as evaluated by ultra-widefield fluorescein angiography[J]. American Journal of Ophthalmology, 2014, 158(1):144-153. doi: 10.1016/j.ajo.2014.03.009
    [44]
    SINGER M, TAN CS, BELL D, et al.. Area of peripheral retinal nonperfusion and treatment response in branch and central retinal vein occlusion[J]. Retina, 2014, 34:1736-1742. doi: 10.1097/IAE.0000000000000148
    [45]
    MUQIT M M, MARCELLINO G R, HENSON D B, et al.. Optos-guided pattern scan laser (Pascal)-targeted retinal photocoagulation in proliferative diabetic retinopathy[J]. Acta Ophthalmologica, 2013, 91:251-258. doi: 10.1111/aos.2013.91.issue-3
    [46]
    SKA M, BERNARDES A B, CARDILLO J A, et al.. Retinal nerve fiber layer thickness profile in normal eyes using third-generation optical coherence tomography[J]. Eye, 2006, 20(4):431-439. doi: 10.1038/sj.eye.6701896
    [47]
    ISHIBAZAWA A, NAGAOKA T, TAKAHASHI A, et al.. Optical coherence tomography angiography in diabetic retinopathy:a prospective pilot study[J]. American Journal of Ophthalmology, 2015, 160(1):35-44. doi: 10.1016/j.ajo.2015.04.021
    [48]
    刘长秀, 张丽红, 张勤.FFA与OCT对糖尿病性黄斑水肿临床诊断的对比与分析[J].中国中医眼科杂志, 2014(4):275-277. http://www.cnki.com.cn/Article/CJFDTotal-ZGKZ201404017.htm

    LIU CH X, ZHANG L H, ZHANG Q. Correlation between optical coherence tomography and fundus fluorescence angiography for assessment of diabetic macular edema[J]. Chinese Journal of Chinese Ophthalmology, 2014(4):275-277.(in Chinese) http://www.cnki.com.cn/Article/CJFDTotal-ZGKZ201404017.htm
    [49]
    罗洁, 杨海军, 李小平.频域OCT与FFA在糖尿病视网膜病变患者中的应用[J].眼科新进展, 2015, 35(5):463-466. http://www.cdmd.cnki.com.cn/Article/CDMD-10403-1014116716.htm

    LUO J, YANG H J, LI X P. Application comparative study on frequency domain OCT and FFA in patients with diabetic retinopathy[J]. Recent Advances in Ophthalmology, 2015, 35(5):463-466.(in Chinese) http://www.cdmd.cnki.com.cn/Article/CDMD-10403-1014116716.htm
    [50]
    SPAIDE R F, JR K J, COONEY M J. Retinal vascular layers imaged by fluorescein angiography and optical coherence tomography angiography[J]. Jama Ophthalmology, 2015, 133(1):45-50. doi: 10.1001/jamaophthalmol.2014.3616
    [51]
    JIA Y L, TAN O, TOKAYER J, et al.. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography[J]. Optics Express, 2012, 20(4):4710-4725. doi: 10.1364/OL.40.002305
    [52]
    TAM J, DHAMDHERE K P, TIRUVEEDHULA P, et al.. Disruption of the retinal parafoveal capillary network in type 2 diabetes before the onset of diabetic retinopathy[J]. Investigative Ophthalmology and Visual Science, 2011, 52(12):9257-9266. doi: 10.1364/OE.20.004710
    [53]
    LOMBARDO M, PARRAVANO M, SERRAO S, et al.. Analysis of retinal capillaries in patients with type 1 diabetes and nonproliferative diabetic retinopathy using adaptive optics imaging[J]. Retina, 2013, 33(8):1630-1639. doi: 10.1167/iovs.11-8481
    [54]
    ARICHIKA S, UJI A, MURAKAMI T, et al.. Correlation of retinal arterial wall thickness with atherosclerosis predictors in type 2 diabetes without clinical retinopathy[J]. British Journal of Ophthalmology, 2016, 69-74. doi: 10.1097/IAE.0b013e3182899326
    [55]
    LIU C, ZHI Y, WANG B, et al.. In vivo super-resolution retinal imaging through virtually structured detection[J]. Journal of Biomedical Optics, 2016, 21(12):120502. http://cn.bing.com/academic/profile?id=a1e42d54a98868ad7281eb3b8148d3fe&encoded=0&v=paper_preview&mkt=zh-cn
    [56]
    ZAMORA G, TRUITT P W, NEMETH S C, et al.. Hyperspectral imag analysis for ophthalmic applications[J]. Proc. SPIE, 2004, 5314:138-149. doi: 10.1117/1.JBO.21.12.120502
    [57]
    LI Q, XUE Y, XIAO G, et al.. New microscopic pushbroom hyperspectral imaging system for application in diabetic retinopathy research[J]. Journal of Biomedical Optics, 2007, 12(6):0640111-0640114. doi: 10.1117/12.530796
    [58]
    TAYYARI F, KHUU L A, FLANAGAN J G, et al.. Retinal blood flow and retinal blood oxygen saturation in mild to moderate diabetic retinopathy[J]. Investigative Ophthalmology and Visual Science, 2015, 56(11):6796-6800. http://cn.bing.com/academic/profile?id=0be76c949ea78893be6b14d474d28414&encoded=0&v=paper_preview&mkt=zh-cn
    [59]
    GAO S S, LIU G J, HUANG D, et al.. Optimization of the split-spectrum amplitude-decorrelation angiography algorithm on a spectral optical coherence tomography system[J]. Optics Letters, 2015, 40(10):2305-2308. doi: 10.1167/iovs.15-17481
    [60]
    李凤鸣.中华眼科学[M].北京:人民卫生出版社, 2005.

    LI F M. Chinese Ophthalmology[M]. Beijing:People's Medical Press, 2005.(in Chinese)
    [61]
    MCBAIN V A, FORRESTER J V, LOIS N. Fundus autofluorescence in the diagnosis of cystoid macular oedema[J]. British Journal of Ophthalmology, 2008, 92(7):946-949. doi: 10.1136/bjo.2007.129957
    [62]
    张新媛, MARK G, 朱晓青, 等.黄斑囊样水肿患者自发荧光与黄斑色素密度的关系[J].眼科, 2010, 19(5):357-360. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=yk201005020

    ZHANG X Y, MARK G, ZHU X Q, et al.. The correlation study of macular autofluorescence and macular pigment in cystoids macular edema[J]. Ophthalmology in China, 2010, 19(5):357-360.(in Chinese) http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=yk201005020
    [63]
    RUSSO A, MORESCALCHI F, COSTAGLIOLA C, et al.. Comparison of smartphone ophthalmoscopy with slit-lamp biomicroscopy for grading diabetic retinopathy[J]. American Journal of Ophthalmology, 2015, 159(2):360-364. doi: 10.1016/j.ajo.2014.11.008
    [64]
    TOY B C, MYUNG D J, HE L, et al.. Smartphone-based dilated fundus photography and near visual acuity testing as inexpensive screening tools to detect referral warranted diabetic eye disease[J]. Retina, 2016, 36(5):1000-1008. doi: 10.1097/IAE.0000000000000955
    [65]
    田蓓.糖尿病视网膜病变全视网膜光凝治疗的几个问题[J].眼科, 2014, 23(4):222-225. http://www.cqvip.com/QK/98276X/201404/662150545.html

    TIAN B. Several problems of photocoagulation for diabetic retinopathy[J]. Ophthalmology in China, 2014, 23(4):222-225.(in Chinese) http://www.cqvip.com/QK/98276X/201404/662150545.html
    [66]
    孙心铨, 王燕琪.激光全视网膜光凝术[J].中国实用眼科杂志, 1998(9):514-516. http://mall.cnki.net/magazine/Article/ZZZY809.000.htm

    SUN X Q, WANG Y Q. Panretinal photocoagulation[J]. Chinese Journal of Practical Ophthalmology, 1998(9):514-516.(in Chinese) http://mall.cnki.net/magazine/Article/ZZZY809.000.htm
    [67]
    STRAUBER S F. Photocoagulation for diabetic macular edema. Early treatment diabetic retinopathy study report number 1[J]. Archives of Ophthalmology, 1985, 103(12):1796-1806. doi: 10.1001/archopht.1985.01050120030015
    [68]
    PORTA M, BANDELLO F. Diabetic retinopathy[J]. Diabetologia, 2002, 45(12):1617-1634. doi: 10.1007/s00125-002-0990-7
    [69]
    WOLBARSHT M L, LANDERS M B. The rationale of photocoagulation therapy for proliferative diabetic retinopathy:a review and a model[J]. Ophthalmic Surgery, 1980, 11(4):235-245. http://cn.bing.com/academic/profile?id=2b4a7a24323dd259876675c5edf2d0cc&encoded=0&v=paper_preview&mkt=zh-cn
    [70]
    STEFÁNSSON E. The therapeutic effects of retinal laser treatment and vitrectomy:A theory based on oxygen and vascular physiology[J]. Acta Ophthalmologic a Scandinavica, 2001, 79(5):435-440. doi: 10.1034/j.1600-0420.2001.790502.x
    [71]
    BRESNICK G H. Diabetic maculopathy:A critical review highlighting diffuse macular edema[J]. Ophthalmology, 1983, 90(11):1301-1317. doi: 10.1016/S0161-6420(83)34388-8
    [72]
    SPRANGER J, HAMMES H P, PREISSNER K T, et al.. Release of the angiogenesis inhibitor angiostatin in patients with proliferative diabetic retinopathy:association with retinal photo-coagulation[J]. Diabetologia, 2000, 43(11):1404-1407. doi: 10.1007/s001250051546
    [73]
    MMK M, HENSON D B, YOUNG L B, et al.. Single-session versus multiple-session pattern scanning laser(Pascal) panretinal photocoagulation in proliferative diabetic retinopathy:the manchester pascal, study[J]. Archives Ophthalmology, 2010, 128(5):525-533. doi: 10.1001/archophthalmol.2010.60
    [74]
    彭志华, 程谷萌, 吴岚.Pascal模式扫描光凝治疗糖尿病视网膜病变的疗效观察[J].国际眼科杂志, 2013, 13(8):1639-1641. doi: 10.3980/j.issn.1672-5123.2013.08.38

    PENG ZH H, CHENG G M, WU L. Observation of clinical efficacy of pattern scan laser photocoagulation on diabetic retinopathy[J]. International Joural of Ophthalmology, 2013, 13(8):1639-1641.(in Chinese) doi: 10.3980/j.issn.1672-5123.2013.08.38
    [75]
    刘卫, 张勇进, 徐格致.频域相干光断层扫描对PASCAL光凝治疗糖尿病性黄斑水肿后视网膜微结构观察[J].中国眼耳鼻喉杂志, 2014, 14(4):218-222. http://www.cnki.com.cn/Article/CJFDTOTAL-YWLC201511051.htm

    LIU W, ZHANG Y J, XU G ZH. In vivo retinal micro-architecture observation after PASCAL photocoagulation treatment in diabetic macular edema by using spectral-domain optical coherence tomography[J]. Chinese Journal of Ophthalmology and Otorhinolaryngology, 2014, 14(4):218-222.(in Chinese) http://www.cnki.com.cn/Article/CJFDTOTAL-YWLC201511051.htm
    [76]
    MUKHEAR A, KHAN M S, JUNEJO M, et al.. Effect of pan retinal photocoagulation on central macular thickness and visual acuity in proliferative diabetic retinopathy[J]. Pakistan Journal of Medical Sciences, 2016;32(1):221-224. http://cn.bing.com/academic/profile?id=a1af5b0efe6a591f359b07a3beceef03&encoded=0&v=paper_preview&mkt=zh-cn
    [77]
    CHAPPELOW A V, TAN K, WAHEED N K, et al.. Panretinal photocoagulation for proliferative diabetic retinopathy:pattern scan laser versus argon laser[J]. American Journal of Ophthalmology, 2012;153(1):137-142. doi: 10.1016/j.ajo.2011.05.035
    [78]
    董如娇, 陈芳, 李冬育, 等.PASCAL激光与氪离子激光治疗糖尿病视网膜病变观察分析[J].中国实用眼科杂志, 2014, 32(7):849-851. http://med.wanfangdata.com.cn/Paper/Detail/PeriodicalPaper_zgsyykzz201407012

    DONG R J, CHEN F, LI D Y, et al.. Clinical analysis of PASCAL laser and Krypton ion laser treatment of diabetic retinopathy[J]. Chinese Journal of Practical Ophthalmology, 2014, 32(7):849-851.(in Chinese) http://med.wanfangdata.com.cn/Paper/Detail/PeriodicalPaper_zgsyykzz201407012
    [79]
    LOCK H J. An update on retinal laser therapy[J]. Clinical and Experimental Optometry, 2011, 94(1):43-51. doi: 10.1111/j.1444-0938.2010.00529.x
    [80]
    KERNT M, CHEUTEU R, VOUNOTRYPIDIS E, et al.. Focal and panretinal photocoagulation with a navigated laser(NAVILAS)[J]. Acta Ophthalmologica, 2011, 89(8):662-664. doi: 10.1111/aos.2011.89.issue-8
    [81]
    CHALAM K V, MURTHY R K, BRAR V, et al.. Evaluation of a novel, non-contact, automated focal laser with integrated(NAVILAS) fluorescein angiography for diabetic macular edema[J]. Middle East African Journal of Ophthalmology, 2012, 19(1):158-162. doi: 10.4103/0974-9233.92134
    [82]
    NEUBAUER A S, LANGER J, LIEGL R, et al.. Navigated macular laser decreases retreatment rate for diabetic macular edema:a comparison with conventional macular laser[J]. Clinical Ophthalmology, 2013, 7(1):121-128. http://cn.bing.com/academic/profile?id=b2958ef7aaeddc2e86c46a7194881206&encoded=0&v=paper_preview&mkt=zh-cn
    [83]
    CHHABLANI J, KOZAK I, BARTESELLI G, et al.. A novel navigated laser system brings new efficacy to the treatment of retinovascular disorders[J]. Oman Journal of Ophthalmology, 2013, 6(1):18-22. doi: 10.4103/0974-620X.111898
    [84]
    SIVAPRASAD S, ELAGOUZ M, MCHUGH D, et al.. Micropulsed diode laser therapy:evolution and clinical applications[J]. Survey of Ophthalmology, 2010, 55(6):516-530. doi: 10.1016/j.survophthal.2010.02.005
    [85]
    DORIN G. Subthreshold and micropulse diode laser photocoagulation[J]. Seminars in Ophthalmology, 2003, 18(3):147-153. doi: 10.1076/soph.18.3.147.29812
    [86]
    GAO X J, XING D. Molecular mechanisms of cell proliferation induced by low power laser irradiation[J]. Journal of Biomedical Science, 2009, 16(4):doi: 10.1186/1423-0127-16-4.
    [87]
    SRAMEK C, MACKANOS M, SPITLER R, et al.. Non-damaging retinal phototherapy:dynamic range of heat shock protein expression[J]. Investigative Ophthalmology and Visual Science, 2011, 52(3):1780-1787. doi: 10.1167/iovs.10-5917
    [88]
    LUTTRULL J K, MUSCH D C, MAINSTER M A. Subthreshold diode micropulse photocoagulation for the treatment of clinically significant diabetic macular edema[J]. British Journal of Ophthalmology, 2005, 89(1):74-80. doi: 10.1136/bjo.2004.051540
    [89]
    LUTTRULL J K, GIORGIO D. Subthreshold diode micropulse laser photocoagulation(SDM) as invisible retinal phototherapy for diabetic macular edema:a review[J]. Current Diabetes Reviews, 2012, 8(4):274-284. doi: 10.2174/157339912800840523
    [90]
    LAURSEN M L, MOELLER F, SANDER B, et al.. Subthreshold micropulse diode laser treatment in diabetic macular edema[J]. British Journal of Ophthalmology, 2004, 88(9):1173-1179. doi: 10.1136/bjo.2003.040949
    [91]
    LUTTRULL J K, MUSCH D C, SPINK C A. Subthreshold diode micropulse panretinal photocoagulation for proliferative diabetic retinopathy[J]. Eye, 2008, 22(5):607-612. doi: 10.1038/sj.eye.6702725
    [92]
    FIGUEIRA J, KHAN J, NUNES S, et al.. Prospective randomized controlled trial comparing sub-threshold micropulse diode laser photocoagulation and conventional green laser for clinically significant diabetic macular edema[J]. British Journal of Ophthalmology, 2009, 93(10):1341-1344. doi: 10.1136/bjo.2008.146712
    [93]
    DPHIL R J C F, FRANZCO G R, FRANZCO H S N, et al.. Pilot randomized trial of a nanopulse retinal laser versus conventional photocoagulation for the treatment of diabetic macular oedema[J]. Clinical and Experimental Ophthalmology, 2012, 40(6):604-610. doi: 10.1111/ceo.2012.40.issue-6
    [94]
    PELOSINI L, HAMILTON R, MOHAMED M, et al.. Retina rejuvenation therapy for diabetic macular edema:a pilot study[J]. Retina, 2013, 33(3):548-558. doi: 10.1097/IAE.0b013e3182670fea
    [95]
    PARK Y, SEIFERT E, ROH Y J, et al.. Tissue response of selective retina therapy by means of a feedback-controlled energy ramping mode[J]. Clinical and Experimental Ophthalmology, 2015, 42(9):846-855. http://cn.bing.com/academic/profile?id=f06f94ef7c320aa8dbff26da8c1f1426&encoded=0&v=paper_preview&mkt=zh-cn
    [96]
    REDDY S, HU A, SCHWARTZ S D. Ultra wide field fluorescein angiography guided targeted retinal photocoagulation(TRP)[J]. Seminars in Ophthalmology, 2009, 24(1):9-14. doi: 10.1080/08820530802519899
    [97]
    SATO Y, KOJIMAHARA N, KITANO S, et al.. Multicenter randomized clinical trial of retinal photocoagulation for preproliferative diabetic retinopathy[J]. Japanese Journal of Ophthalmology, 2012, 56(1):52-59. doi: 10.1007/s10384-011-0095-2
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(2)  / Tables(2)

    Get Citation
    PDF
    XML
    Article views(4100) PDF downloads(206) Cited by()
    Proportional views
    Related

    Copyright© 2012 Editorial Office of Chinese Optics    吉ICP备11002662号

    Address: No. 3888 Southeast Lake Road, Changchun City, Jilin ProvinceTel: 投稿问题：0431-84627061（李老师）；财务问题：0431-86176852（王老师）；邮寄及发行：0431-86176862（张老师）

    Email: chineseoptics@ciomp.ac.cnChina Pos: 130033

    Supported by: Beijing Renhe Information Technology Co. Ltd  support: info@rhhz.net

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return