Volume 11 Issue 5
Oct.  2018
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Chinese Optics  > 2018  >  11(5): 773-778.
DONG Li-dan, WEI Chang-ping, LI Zhong-tian, WANG Feng-ming. Preparation and properties of nano-chitosan composites[J]. Chinese Optics, 2018, 11(5): 773-778. doi: 10.3788/CO.20181105.0773
Citation: DONG Li-dan, WEI Chang-ping, LI Zhong-tian, WANG Feng-ming. Preparation and properties of nano-chitosan composites[J]. Chinese Optics, 2018, 11(5): 773-778. doi: 10.3788/CO.20181105.0773
shu

Preparation and properties of nano-chitosan composites

  • 1.

    School of Materials Science and Engineering, Changchun University of Science and Tech., Changchun 130022, China

  • 2.

    School of drug and food, Changchun Medical College, Changchun 130031, China

  • 3.

    China Water Northeastern Investigation, Design and Research Co., Ltd, Changchun 130061, China

Funds:

China Association for Science and Technology "Overseas Intelligence Service Action Plan" 07064

The Education Department of Jilin Provincial "The 12th Five-year Scientific and Technological Research Project" 【2013】36

More Information
  • Corresponding author: WEI Chang-ping, E-mail:changpingwei@hotmail.com
  • Received Date: 09 Apr 2018
  • Rev Recd Date: 15 May 2018
  • Publish Date: 01 Oct 2018
    Abstract
  • In order to improve the water soluble and the hemostatic performance of chitosan (CS), chitosan is nano-sized and an antibacterial Ag+ and coagulation-assisted Ca2+ are introduced to prepare a nano-chitosan metal ion composite hemostatic material. Firstly, nano-chitosan (nmCS) is prepared by ion exchange method, and AgNO3 and saturated CaCl2 solution are added respectively to obtain nmCS-Ag, nmCS-Ca and nmCS-Ag-Ca composites. Then, the structure of the composite is characterized by means of FTIR, XRD and SEM. Finally, the coagulation and hemostatic properties of the complex are tested. The results show that the characteristic absorption peak of nano-chitosan sodium salt appeared at the modified chitosan IR spectrum at 1 647 cm-1 and 1 560 cm-1. The nano-chitosan composited with metal ions show the crystal characteristics of Ag+ and Ca2+ in the XRD pattern. The SEM shows that partial Ag+ precipitates in nmCS-Ag, and the composite effect of nmCS-Ca is better. The coagulation and hemostasis of nmCS-Ag-Ca is better than that of nmCS-Ag and nmCS-Ca, while the coagulation and hemostasis of nmCS-Ag and nmCS-Ca are better than that of nmCS. The test results show that the nano-chitosan metal ion composite hemostatic material has been successfully prepared.

     

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    • References(14)
  • [1]
    PANWAR P, LAMOUR G, MACKENZIE N C W, et al..Changes in structural-mechanical properties and degradability of collagen during aging-associated modifications[J]. Journal of Biological Chemistry, 2015, 290(38):23291-23306. doi: 10.1074/jbc.M115.644310
    [2]
    SALGADO C L, GRENHO L, FERNANDES M H, et al.. Biodegradation, biocompatibility, and osteoconduction evaluation of collagen Nanohydroxyapatite cryogels for bone tissue regeneration[J]. Journal of Biomedical Materials Research Part A, 2016, 104(1):57-70. doi: 10.1002/jbm.a.35540
    [3]
    GU RL, SUN WZ, ZHOU H, et al.. The performance of a fly-larva shell-derived chitosan sponge as an absorbable surgical hemostatic agent[J]. Biomaterials, 2010, 31(6):1270-1277. doi: 10.1016/j.biomaterials.2009.10.023
    [4]
    李学军, 孙园园.不同生物止血材料研究进展及复合型止血材料的临床应用[J].中国组织工程研究与临床康复, 2011, 15(51):9671-9674. doi: 10.3969/j.issn.1673-8225.2011.51.041

    LI X J, SUN Y Y. Advances in various biomaterials for hemostasis and clinical application of compound materials for hemostasis[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2011, 15(51):9671-9674.(in Chinese) doi: 10.3969/j.issn.1673-8225.2011.51.041
    [5]
    胡帼颖, 顾汉卿.止血剂基础与临床应用研究新进展[J].透析与人工器官, 2010, 21(2):29-35. http://d.old.wanfangdata.com.cn/Periodical/txyrgqg201002007

    HU G Y, GU H Q. New research on the basis and clinical application of hemostatic agents[J]. Chinese J. Dial. & Artif. Organs, 2010, 21(2):29-35.(in Chinese) http://d.old.wanfangdata.com.cn/Periodical/txyrgqg201002007
    [6]
    ONG S Y, WU J, MOOCHHALA S M, et al..Development of achitosan-based wound dressing with improved hemostatic and antimicrobial properties[J]. Biomaterials, 2008, 29(32):4323-4332. doi: 10.1016/j.biomaterials.2008.07.034
    [7]
    杜建华, 刘彦伟, 李园园.纳米颗粒增强酮基摩擦材料的摩擦学性能[J].光学精密工程, 2013, 21(10):2581-2586. http://kns.cnki.net/KCMS/detail/detail.aspx?filename=GXJM201310016&dbname=CJFD&dbcode=CJFQ

    DU J H, LIU Y W, LI Y Y. Nanoparticles enhance the tribological properties of ketone-based friction materials[J]. Opt. Precision Eng., 2013, 21(10):2581-2586.(in Chinese) http://kns.cnki.net/KCMS/detail/detail.aspx?filename=GXJM201310016&dbname=CJFD&dbcode=CJFQ
    [8]
    孙磊.高粘度壳聚糖止血材料的制备及其应用性研究[D].北京: 中央民族大学, 2012. http://cdmd.cnki.com.cn/Article/CDMD-10052-1012416220.htm

    SUN L. Preparation and application of high viscosity chitosan hemostatic material[D]. Beijing: Minzu University of China, 2012.(in Chinese) http://cdmd.cnki.com.cn/Article/CDMD-10052-1012416220.htm
    [9]
    STEFANI I, COOPER-WHITE J J. Development of an in-process UV-crosslinked, electrospun PCL/a PLA-co-TMC composite polymer for tubular tissue engineering applications[J]. Acta Biomaterialia, 2016, 36:231-240. doi: 10.1016/j.actbio.2016.03.013
    [10]
    丁萍, 黄可龙, 刘艳飞, 等.壳聚糖衍生物与Ca(Ⅱ)螯合反应的动力学及机理研究[J].动能材料, 2008, 39(6):961-964. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=gncl200806024

    DING P, HUANG K L, LIU Y F, et al.. Kinetics and mechanism research of chitosan derivatives with Ca(Ⅱ) chelate reaction[J]. Kinetic Energy Materials, 2008, 39(6):961-964. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=gncl200806024
    [11]
    ZHOU Z L, SHANG H B, SUI Y X, et al.. Useful way to compensate for intrinsic birefringence caused by calcium fluoride in optical lithography systems[J]. Chinese Optic Letters, 2018, 16(3), 032201:1-5. http://www.cnki.com.cn/Article/CJFDTotal-GXKB201803016.htm
    [12]
    RODRIGUEZ N R M, DAS S, KAUFMAN Y, et al.. Mussel adhesive protein provides cohesive matrix for collagen type-1α[J]. Biomaterials, 2015, 51:51-57. doi: 10.1016/j.biomaterials.2015.01.033
    [13]
    FANG J Q, JIANG L, CAO Q, et al.. Doping transition metal ions as a method for enhancement of ablation rate in femtosecond laser irradiation of silicate glass[J]. Chinese Optic Letters, 2014, 12, 120402:1-5. http://www.opticsinfobase.org/col/abstract.cfm?uri=col-12-12-121402
    [14]
    许辉, 张俊举, 袁轶慧, 等.红外与可见光图像融合系统的探测概率[J].光学精密工程, 2013, 21(12):3205-3213. http://d.old.wanfangdata.com.cn/Periodical/gxjmgc201312030

    XU H, ZHANG J J, YUAN Y H, et al.. Detection probability of infrared and visible image fusion system[J]. Opt. Precision Eng., 2013, 21(12):3205-3213.(in Chinese) http://d.old.wanfangdata.com.cn/Periodical/gxjmgc201312030
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