Design of multi-focus intraocular lenses
-
摘要: 运用Zemax光学设计软件构建Liou-Brennan眼模型,设计了增大焦深的非球面、折射型多焦点和衍射型多焦点人工晶体,并用点列图和视锐度分析了所设计的人工晶体的光学质量。对于非球面人工晶体,在3 mm瞳孔下,当人眼无球差时,最佳视锐度相当高,但焦深仅为1.4 m-1;当人眼球差为0.4时,最佳视锐度可达0.9,焦深达2.2 m-1,同时在整个焦深范围内视觉质量均优越。对于衍射型和折射型多焦点人工晶体,在明视条件下,虽然视远和视近时视觉质量良好,但是中间距离的视锐度0.5。衍射型多焦点人工晶体只有81%的光能用于成像,远近焦点能量均分,且与瞳孔大小无关;折射型多焦点人工晶体的远近焦点能量与瞳孔大小相关。设计的人工晶体均能增大人眼的焦深,但各有优缺点,临床上应该酌情选用。Abstract: The Liou-Brennan eye model is constructed using the optical design software ZEMAX. The Depth of Focus(DOF), extended Intraocular Lenses(IOL) that includes aspherical IOL, refractive multifocal IOL and diffractive multifocus IOL are included in the design. The optical performance of the pseudophakic eye for the designed IOLs is analyzed for both the spot diagram and visual acuity. For the pseudophakic eye with a 3 mm pupil, when the spherical aberration is fully corrected by the aspherical IOL, the best visual acuity reaches 1.2 with a DOF of only 1.4 m-1. When the spherical aberration is 0.4, the best visual acuity is 0.9 with a DOF as high as 2.2 m-1. With the implantation of refractive or diffractive multifocus IOLs, the pseudophakic eye has fairly good distant and near vision, while the intermediate vision is lower than 0.5. Diffractive multifocal IOL allows 81% input energy to image and the energy distribution is not affected by the pupil size. The energy distribution of the refractive multifocal IOL is dependent on the pupil diameter. The aspherical IOL, refractive multifocal IOL and diffractive multifocal IOL can extend DOF after surgery. However, they all have advantages and disadvantages, which should be taken into consideration under clinical conditions.
-
Key words:
- ophthalmic optics /
- Intraocular Lenses(IOL) /
- Depth of Focus(DOF) /
- multi-focus /
- eye model
-
[1] DAVISON J A,SIMPSON M J. History and development of the apodized diffractive intraocular lens[J]. J.Cataract Refract. Surg.,2006,32(5):849-858. [2] 饶丰. 基于个性化眼模型的人工晶体设计及其特性研究.天津:南开大学光学研究所,2010. RAO F. Study on the design and the performance of intraocular lenses based on individual eye models. Tianjin:Institute of Modern Optics,Nankai University,2010.(in Chinese) [3] NEGISHI K,OHNUMA K,IKEDA T,et al.. Visual simulation of retinal images through a decentered monofocal and a refractive multifocal Intraocular Lens[J]. Jpn. J. Ophthalmol.,2005,49(4):281-286. [4] PIEH S,MARVAN P,LACKNER B,et al.. Quantitative performance of bifocal and multifocal intraocular lenses in a model eye:point spread function in multifocal intraocular lenses[J]. Arch. Ophthalmol.,2002,120(1):23-28. [5] 王幼生,廖瑞瑞,刘泉,等.现代眼视光学[M]. 广州:广东科技出版社,2006. WANG Y SH,LIAO R R,LIN Q,et al.. Advanced Vision Optics[M]. Guangzhou:Guangdong Science Press,2006.(in Chinese) [6] HARMAN F E,MALING S,KAMPOUGERIS G,et al.. Comparing the 1CU accommodative, multifocal, and monofocal intraocular lenses:a randomized trial[J]. Ophthalmology,2008,115(6):993-1001. [7] EPPIG T,SCHOLZ K,LOFFLER A,et al.. Effect of decentration and tilt on the image quality of aspheric intraocular lens designs in a model eye[J]. J.Cataract Refract. Surg.,2009,35(6):1091-1100. [8] RAO F,WANG Z Q,WANG Y,et al.. Achromatic customized intraocular lens based on an individual pseudophakic eye model[J]. Optik,2010,121(4):366-372. [9] ZLOTNIK A,YAISH S B,YEHEZKEL O. Extended depth of focus contact lenses for presbyopia[J]. Opt. Lett.,2009,34(14):2219-2221. [10] LIOU H L,BRENNAN N A. Anatomically accurate, finite model eye for optical modeling[J]. J. Opt. Soc. Am. A,1997,14(8):1684-1695. [11] LIU T,WANG Z Q,WANG Y,et al.. The study of the effects of higher-order aberrations on human contrast sensitivity with white-light retinal aerial image modulation[J]. Optik,2010,121(12):1116-1122. [12] WANG W,WANG Z,WANG Y. Measurements of AIM for visible wavelength based on individual eye model[J]. Chin. Phys. Lett.,2006,23(12):3263-3266. [13] 徐广第.眼科屈光学 [M].第4版.北京:军事医学科学出版社,2005:129. XU G D. Ophthalmology Refraction[M]. 4th ed. Beijing:Military Medical Science Press,2005.(in Chinese) [14] PACKERr M,HOFFMAN R S,HOWARD F. Refractive Lens Surgery[M]. Berlin:Springer-Verlag,2005. [15] 谭少健,梁皓,李霞,等. 多焦点人工晶状体眼早期视觉质量的研究[J]. 眼科,2005,14(1):17-22. TAN SH J,LIANG H,LI X,et al.. Early postoperative visual function after multifocal intraocular lens implantation[J]. Ophthalmol. Chin.,2005,14(1):17-22.(in Chinese)
点击查看大图
计量
- 文章访问数: 2959
- HTML全文浏览量: 514
- PDF下载量: 1065
- 被引次数: 0